Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway

• Principais autores: Afshin Ebrahimpour (Autor), Min Wang (Autor), Li Li (Autor), Anil G. Jegga (Autor), Mark D. Bonnen (Autor), N. Tony Eissa (Autor), Ganesh Raghu (Autor), Soma Jyothula (Autor), Farrah Kheradmand (Autor), Nicola A. Hanania (Autor), Ivan O. Rosas (Autor), Yohannes T. Ghebre (Autor)
• Formato: Livro
• Publicado em: BMC, 2021-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Introduction Idiopathic pulmonary fibrosis (IPF) is an orphan disease characterized by progressive loss of lung function resulting in shortness of breath and often death within 3-4 years of diagnosis. Repetitive lung injury in susceptible individuals is believed to promote chronic oxidative...