DNA Cleavage and Cytotoxic Activity of Copper(II) Complexes Based on Reduced Schiff Bases Derived From Salicylaldehyde and Amino Acids

• Main Authors: Korcová Jana (Author), Húserková Mária (Author), Lintnerová Lucia (Author), Valentová Jindra (Author)
• 格式: 圖書
• 出版: Sciendo, 2024-03-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Metal complexes, which, under physiologic conditions, show redox properties and are able to bind to DNA, are great tools to cleave the DNA chain. This aspect is of great importance for their use as antineoplastic drugs. We synthesized ligands derived from short-chain amino acids and from salicylalde...