A Therapeutic Challenge: Liddle's Syndrome Managed with Amiloride during Pregnancy

• Main Authors: Amelia Caretto (Author), Liviana Primerano (Author), Francesca Novara (Author), Orsetta Zuffardi (Author), Stefano Genovese (Author), Maurizio Rondinelli (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liddle's syndrome (LS) is a rare heritable form of hypertension that often affects young patients. It is caused by gain-of-function mutations of the kidney epithelial sodium channel (ENaC) and it is classically associated with hypokalemia and suppression of renin and aldosterone. LS is characte...