Jiyuan oridonin A induces differentiation of acute myeloid leukemia cells including leukemic stem-like cells

• Main Authors: Fahui Li (Author), Congying Gao (Author), Xueming Li (Author), Jiangyun Wang (Author), Yao Zhao (Author), Yu Ke (Author), Ying Liu (Author), Hong-Min Liu (Author), Zhenbo Hu (Author), Liuya Wei (Author), Zhe-Sheng Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute myeloid leukemia (AML) is an aggressive form of hematological neoplasia characterized by failure of myeloid differentiation. AML is a leading cause of death from leukemia. Cytarabine chemotherapy resistance is a major source of refractory/relapsed AML. A major obstacle to the successful treatm...