Mass balance and pharmacokinetic characterization of zavegepant in healthy male subjects

• Váldodahkkit: Rajinder Bhardwaj (Dahkki), Mary Donohue (Dahkki), Jennifer Madonia (Dahkki), Matt S. Anderson (Dahkki), Kyle Matschke (Dahkki), Richard Bertz (Dahkki), Robert Croop (Dahkki), Jing Liu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wiley, 2024-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Zavegepant, a high‐affinity, selective, small‐molecule calcitonin gene‐related peptide receptor antagonist, is approved as a nasal spray for acute treatment of migraine in adults. This phase I, open‐label, single‐center, single‐period, nonrandomized study in six healthy male subjects assess...