Investigation of Alogliptin-Loaded In Situ Gel Implants by 2³ Factorial Design with Glycemic Assessment in Rats

• मुख्य लेखकों: Tarek M. Ibrahim (लेखक), Margrit M. Ayoub (लेखक), Hany M. El-Bassossy (लेखक), Hanan M. El-Nahas (लेखक), Eman Gomaa (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The aim of the study was to design injectable long-acting poly (lactide-co-glycolide) (PLGA)-based in situ gel implants (ISGI) loaded with the anti-diabetic alogliptin. Providing sustained therapeutic exposures and improving the pharmacological responses of alogliptin were targeted for achieving red...