Experimental pharmacokinetics of a new antiparkinsonian drug ADK-1113

• Main Authors: O. Yu. Kravtsova (Author), D. A. Dvoryaninov (Author), G. B. Kolyvanov (Author), A. A. Litvin (Author), O. G. Gribakina (Author), V. P. Zherdev (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pharmacokinetics of a new antiparkinsonian drug ADK-1113 after single intravenous and intragastric administrations in mice at doses of 10 and 20 mg/kg was studied. The absolute bioavailability was 10.1-16.3 % that indicates on potential possibility of preparing a dosage form for oral administrat...