Influence of Gender, Body Mass Index, and Age on the Pharmacokinetics of Itraconazole in Healthy Subjects: Non-Compartmental Versus Compartmental Analysis

Influence of Gender, Body Mass Index, and Age on the Pharmacokinetics of Itraconazole in Healthy Subjects: Non-Compartmental Versus Compartmental Analysis

Itraconazole is a triazole antifungal agent with highly variable pharmacokinetics, with not yet fully identified factors as the source of this variability. Our study aimed to examine the influence of body mass index, gender, and age on the first dose pharmacokinetics of itraconazole in healthy subje...

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Main Authors: Milijana N. Miljković (Author), Nemanja Rančić (Author), Aleksandra Kovačević (Author), Bojana Cikota-Aleksić (Author), Ivan Skadrić (Author), Vesna Jaćević (Author), Momir Mikov (Author), Viktorija Dragojević-Simić (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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