Development of carbon monoxide-releasing molecules conjugated to polysaccharides (glyco-CORMs) for delivering CO during obesity

• Main Authors: Shruti Mohan (Author), Louis-Antoine Barel (Author), Djamal Eddine Benrahla (Author), Bernard Do (Author), Qiyue Mao (Author), Hiroaki Kitagishi (Author), Michael Rivard (Author), Roberto Motterlini (Author), Roberta Foresti (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metal carbonyls have been developed as carbon monoxide-releasing molecules (CO-RMs) to deliver CO for therapeutic purposes. The manganese-based CORM-401 has been recently reported to exert beneficial effects in obese animals by reducing body weight gain, improving glucose metabolism and reprogrammin...