Heparan sulfate targeting strategy for enhancing liposomal drug accumulation and facilitating deep distribution in tumors

• Main Authors: Ping-Hsueh Kuo (Author), Yi-Hsien Teng (Author), Ann-Lun Cin (Author), Wen Han (Author), Pei-Wan Huang (Author), Lily Hui-Ching Wang (Author), Yu-Ting Chou (Author), Jia-Ling Yang (Author), Yun-Long Tseng (Author), Minhsiung Kao (Author), Margaret Dah-Tsyr Chang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanoparticles (NPs), such as liposomes, effectively evade the severe toxicity of unexpected accumulation and passively shuttle drugs into tumor tissues by enhanced permeability and retention. In the case of non-small cell lung cancer and pancreatic ductal adenocarcinoma, cancer-associated fibroblast...