Hippocampal insulin signaling and neuroprotection mediated by physical exercise in Alzheimer´s Disease

• Main Authors: Gabriel Keine Kuga (Author), José Diego Botezelli (Author), Rafael Calais Gaspar (Author), Ricardo José Gomes (Author), José Rodrigo Pauli (Author), José Alexandre Curiacos de Almeida Leme (Author)
• Format: Book
• Published: Universidade Estadual Paulista (UNESP), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Epidemiological studies indicate continuous increases in the prevalence of Alzheimer's Disease (AD) in the next few decades. The key feature of this disease is hippocampal neurodegeneration. This structure has an important role in learning and memory. Intense research efforts have soug...