Spliceosomal components protect embryonic neurons from R-loop-mediated DNA damage and apoptosis

• 主要な著者: Shelly Sorrells (著者), Sara Nik (著者), Mattie Casey (著者), Rosannah C. Cameron (著者), Harold Truong (著者), Cristhian Toruno (著者), Michelle Gulfo (著者), Albert Lowe (著者), Cicely Jette (著者), Rodney A. Stewart (著者), Teresa V. Bowman (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2018-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

RNA splicing factors are essential for the viability of all eukaryotic cells; however, in metazoans some cell types are exquisitely sensitive to disruption of splicing factors. Neuronal cells represent one such cell type, and defects in RNA splicing factors can lead to neurodegenerative diseases. Th...