Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway

• Main Authors: Tong Liu (Author), Yujing Xia (Author), Jingjing Li (Author), Sainan Li (Author), Jiao Feng (Author), Liwei Wu (Author), Rong Zhang (Author), Shizan Xu (Author), Keran Cheng (Author), Yuqing Zhou (Author), Shunfeng Zhou (Author), Weiqi Dai (Author), Kan Chen (Author), Fan Wang (Author), Jie Lu (Author), Yingqun Zhou (Author), Chuanyong Guo (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. Shikonin possesses anti-inflammatory effects. However, its function in concanavalin A-induced acute liver injury remains uncertain. The aim of the present study was to investigate the functions of shikonin and its mechanism of protection on ConA-induced acute liver injury. Materials and M...