Bio-mimetic drug delivery systems designed to help the senior population reconstruct melatonin plasma profiles similar to those of the healthy younger population

• Main Authors: Ying Li (Author), Liuyi Wang (Author), Li Wu (Author), Xueju Zhang (Author), Xue Li (Author), Zhen Guo (Author), Haiyan Li (Author), Peter York (Author), Shuangying Gui (Author), Jiwen Zhang (Author)
• Format: Book
• Published: Elsevier, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The secretion of melatonin (MT) is obviously different in the younger and the senior sectors of the population, and the maximum plasma concentration of seniors is only half of that in the younger population group. If exogenous MT can be supplied to senior citizens based on the secretion rate and amo...