Dual Action of Memantine in Alzheimer Disease: A Hypothesis

Objective: In this study, we proposed a hypothesis to explain the mechanisms of memantine action in treating Alzheimer disease (AD). Memantine may reduce the expression of amyloid precursor protein and tau protein, as well as acting as an antagonist of N-methyl-d-aspartate receptors in the brain. Re...

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Main Authors: Tzong-Yuan Wu (Author), Chih-Ping Chen (Author)
Formato: Livro
Publicado em: Elsevier, 2009-09-01T00:00:00Z.
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3rd Floor Main Library

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