Dual Action of Memantine in Alzheimer Disease: A Hypothesis

• मुख्य लेखकों: Tzong-Yuan Wu (लेखक), Chih-Ping Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2009-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: In this study, we proposed a hypothesis to explain the mechanisms of memantine action in treating Alzheimer disease (AD). Memantine may reduce the expression of amyloid precursor protein and tau protein, as well as acting as an antagonist of N-methyl-d-aspartate receptors in the brain. Re...