Direct activation of platelets by addition of CaCl2 leads coagulation of platelet-rich plasma

• Main Authors: Toshihisa Toyoda (Author), Kazushige Isobe (Author), Tetsuhiro Tsujino (Author), Yasuo Koyata (Author), Fumitaka Ohyagi (Author), Taisuke Watanabe (Author), Masayuki Nakamura (Author), Yutaka Kitamura (Author), Hajime Okudera (Author), Koh Nakata (Author), Tomoyuki Kawase (Author)
• Format: Book
• Published: SpringerOpen, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Based on the notion that full activation of platelets is required for a growth factor release, in regenerative dentistry, platelet-rich plasma (PRP) in liquid form is usually clotted by addition of CaCl2 in glassware before topical implantation. However, there has been no evidenc...