Aspiration pneumonia induces muscle atrophy in the respiratory, skeletal, and swallowing systems

• Main Authors: Riyo Komatsu (Author), Tatsuma Okazaki (Author), Satoru Ebihara (Author), Makoto Kobayashi (Author), Yoko Tsukita (Author), Mayumi Nihei (Author), Hisatoshi Sugiura (Author), Kaijun Niu (Author), Takae Ebihara (Author), Masakazu Ichinose (Author)
• Format: Book
• Published: Wiley, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Repetition of the onset of aspiration pneumonia in aged patients is common and causes chronic inflammation. The inflammation induces proinflammatory cytokine production and atrophy in the muscles. The proinflammatory cytokines induce muscle proteolysis by activating calpains and...