Kinetic‐Pharmacodynamic Model of Platelet Time Course in Patients With Moderate‐to‐Severe Atopic Dermatitis Treated With Oral Janus Kinase 1 Inhibitor Abrocitinib

The oral Janus kinase 1 (JAK1) inhibitor abrocitinib reduced signs and symptoms of atopic dermatitis (AD) in a placebo‐controlled, randomized, double‐blind, phase IIb trial (dose range 10-200 mg). A kinetic‐pharmacodynamic (K‐PD) model consisting of proliferation, maturation, and blood circulation c...

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Main Authors: Elena Soto (Author), Christopher Banfield (Author), Pankaj Gupta (Author), Mark C. Peterson (Author)
Format: Book
Published: Wiley, 2020-10-01T00:00:00Z.
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3rd Floor Main Library

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