<i>Amicis Omnia Sunt Communia</i>: NF-κB Inhibition as an Alternative to Overcome Osteosarcoma Heterogeneity

• Main Authors: Mariana Medeiros (Author), Sophia Guenka (Author), David Bastos (Author), Karla Laissa Oliveira (Author), María Sol Brassesco (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor heterogeneity poses a significant challenge in osteosarcoma (OS) treatment. In this regard, the "omics" era has constantly expanded our understanding of biomarkers and altered signaling pathways (i.e., PI3K/AKT/mTOR, WNT/β-catenin, NOTCH, SHH/GLI, among others) involved in OS pathoph...