Downstream processing of spray-dried ASD with hypromellose acetate succinate - Roller compaction and subsequent compression into high ASD load tablets

Despite wide commercial application of hypromellose acetate succinate (HPMCAS) in spray-dried amorphous solid dispersion (ASD) drug products, little information is available in the references on downstream processing of spray-dried dispersions with HPMCAS. Poor flow and high dilution factor are a ch...

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Main Authors: Andreas Sauer (Author), Shogo Warashina (Author), Saurabh M Mishra (Author), Ilja Lesser (Author), Katja Kirchhöfer (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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