Downstream processing of spray-dried ASD with hypromellose acetate succinate - Roller compaction and subsequent compression into high ASD load tablets

• Asıl Yazarlar: Andreas Sauer (Yazar), Shogo Warashina (Yazar), Saurabh M Mishra (Yazar), Ilja Lesser (Yazar), Katja Kirchhöfer (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Despite wide commercial application of hypromellose acetate succinate (HPMCAS) in spray-dried amorphous solid dispersion (ASD) drug products, little information is available in the references on downstream processing of spray-dried dispersions with HPMCAS. Poor flow and high dilution factor are a ch...