Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice

• Hauptverfasser: Antoine Rohrbach (Verfasst von), Emilie Caron (Verfasst von), Rafik Dali (Verfasst von), Maxime Brunner (Verfasst von), Roxane Pasquettaz (Verfasst von), Irina Kolotuev (Verfasst von), Federico Santoni (Verfasst von), Bernard Thorens (Verfasst von), Fanny Langlet (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2021-11-01T00:00:00Z.
• Schlagworte: article
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Objectives: Glucokinase (GCK) is critical for glucosensing. In rats, GCK is expressed in hypothalamic tanycytes and appears to play an essential role in feeding behavior. In this study, we investigated the distribution of GCK-expressing tanycytes in mice and their role in the regulation of energy ba...