IDF-11774 Induces Cell Cycle Arrest and Apoptosis by Inhibiting HIF-1α in Gastric Cancer

• Hoofdauteurs: Won-Ho Kim (Auteur), Min-Jee Kim (Auteur), Jun-O Jin (Auteur), Peter C. W. Lee (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Hypoxia-inducible factor-1 alpha (HIF-1α) is a regulatory factor of intracellular oxygen supersession. The expression or increased activity of HIF-1α is closely related to various human cancers. Previously, IDF-11774 was demonstrated to inhibit HSP70 chaperone activity and suppress the accumulation...