Identification of an Antimicrobial Peptide from the Venom of the Trinidad Thick-Tailed Scorpion <i>Tityus trinitatis</i> with Potent Activity against ESKAPE Pathogens and <i>Clostridioides difficile</i>

• Main Authors: Milena Mechkarska (Author), Taylor S. Cunning (Author), Megan G. Taggart (Author), Nigel G. Ternan (Author), Jérôme Leprince (Author), Laurent Coquet (Author), Thierry Jouenne (Author), Jordi Tena-Garcés (Author), Juan J. Calvete (Author), J. Michael Conlon (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Envenomation by the Trinidad thick-tailed scorpion <i>Tityus trinitatis</i> may result in fatal myocarditis and there is a high incidence of acute pancreatitis among survivors. Peptidomic analysis (reversed-phase HPLC followed by MALDI-TOF mass spectrometry and automated Edman degradatio...