Restoring Wnt signaling in a hormone-simulated postpartum depression model remediated imbalanced neurotransmission and depressive-like behaviors

• Main Authors: Binglu Ye (Author), Yawei Yuan (Author), Rui Liu (Author), Haitao Zhou (Author), Yujie Li (Author), Zhihao Sheng (Author), Tianyu Li (Author), Bing Zhang (Author), Zhendong Xu (Author), Yang Li (Author), Zhiqiang Liu (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Postpartum depression (PPD) is a prevalent mental disorder that negatively impacts mothers and infants. The mechanisms of vulnerability to affective illness in the postpartum period remain largely unknown. Drastic fluctuations in reproductive hormones during the perinatal period...