New insight into the anti-liver fibrosis effect of multitargeted tyrosine kinase inhibitors: from molecular target to clinical trials

• Main Authors: Kai eQu (Author), Zichao eHuang (Author), Ting eLin (Author), Sinan eLiu (Author), Hulin eChang (Author), Zhaoyong eYan (Author), Hongxin eZhang (Author), Chang eLiu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tyrosine kinases (TKs) is a family of tyrosine protein kinases with important functions in the regulation of a broad variety of physiological cell processes. Overactivity of TK disturbs cellular homeostasis and has been linked to the development of certain diseases, including various fibrotic diseas...