Helminth infection modulates systemic pro-inflammatory cytokines and chemokines implicated in type 2 diabetes mellitus pathogenesis.

• Main Authors: Anuradha Rajamanickam (Author), Saravanan Munisankar (Author), Chandrakumar Dolla (Author), Pradeep A Menon (Author), Kannan Thiruvengadam (Author), Thomas B Nutman (Author), Subash Babu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The prevalence of helminth infections exhibits an inverse association with the prevalence of Type 2 diabetes mellitus (T2DM), and helminths are postulated to mediate a protective effect against T2DM. However, the biological mechanism behind this effect is not known. AIMS/METHODS:We postul...