Formulation and in vitro evaluation of topical nanosponge-based gel containing butenafine for the treatment of fungal skin infection

• Main Authors: Mohammed Muqtader Ahmed (Author), Farhat Fatima (Author), Md. Khalid Anwer (Author), Elmutasim Osman Ibnouf (Author), Mohd Abul Kalam (Author), Aws Alshamsan (Author), Mohammed F. Aldawsari (Author), Ahmed Alalaiwe (Author), Mohammad Javed Ansari (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the current study, four formulae (BNS1-BNS4) of butenafine (BTF) loaded nanosponges (NS) were fabricated by solvent emulsification technology, using different concentration of ethyl cellulose (EC) and polyvinyl alcohol (PVA) as a rate retarding polymer and surfactant, respectively. Prepared NS we...