Renal Fibrosis in Murine Obstructive Nephropathy Is Attenuated by Depletion of Monocyte Lineage, Not Dendritic Cells

• Auteurs principaux: Yuichi Machida (Auteur), Koichiro Kitamoto (Auteur), Yasukatsu Izumi (Auteur), Masayuki Shiota (Auteur), Junji Uchida (Auteur), Yukimi Kira (Auteur), Tatsuya Nakatani (Auteur), Katsuyuki Miura (Auteur)
• Format: Livre
• Publié: Elsevier, 2010-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract.: The role of renal dendritic cells (DCs) in renal fibrosis is unknown. The present study was conducted to examine the relative role of renal DCs and macrophages in the development of renal fibrosis in murine obstructive nephropathy. CD11c-diphtheria toxin receptor (DTR) transgenic mice and...