Berberine Facilitates Extinction and Prevents the Return of Fear

• Main Authors: Shihao Huang (Author), Yu Zhou (Author), Feilong Wu (Author), Cuijie Shi (Author), He Yan (Author), Liangpei Chen (Author), Chang Yang (Author), Yixiao Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exposure to a catastrophic event or intense stimulation can trigger fear memories, and the threatening memories persist even over a lifetime. Exposure therapy is based on extinction learning and is widely used to treat fear-related disorders, but its effect on remote fear memory is modest. Berberine...