Integrin-Linked Kinase Expression in Human Valve Endothelial Cells Plays a Protective Role in Calcific Aortic Valve Disease

• Auteurs principaux: Sandra Sánchez-Esteban (Auteur), Mercedes Castro-Pinto (Auteur), Alberto Cook-Calvete (Auteur), Paula Reventún (Auteur), María Delgado-Marín (Auteur), Lucía Benito-Manzanaro (Auteur), Ignacio Hernandez (Auteur), José López-Menendez (Auteur), José Luis Zamorano (Auteur), Carlos Zaragoza (Auteur), Marta Saura (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Calcific aortic valve disease (CAVD) is highly prevalent during aging. CAVD initiates with endothelial dysfunction, leading to lipid accumulation, inflammation, and osteogenic transformation. Integrin-linked kinase (ILK) participates in the progression of cardiovascular diseases, such as endothelial...