Integrin-Linked Kinase Expression in Human Valve Endothelial Cells Plays a Protective Role in Calcific Aortic Valve Disease

• मुख्य लेखकों: Sandra Sánchez-Esteban (लेखक), Mercedes Castro-Pinto (लेखक), Alberto Cook-Calvete (लेखक), Paula Reventún (लेखक), María Delgado-Marín (लेखक), Lucía Benito-Manzanaro (लेखक), Ignacio Hernandez (लेखक), José López-Menendez (लेखक), José Luis Zamorano (लेखक), Carlos Zaragoza (लेखक), Marta Saura (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Calcific aortic valve disease (CAVD) is highly prevalent during aging. CAVD initiates with endothelial dysfunction, leading to lipid accumulation, inflammation, and osteogenic transformation. Integrin-linked kinase (ILK) participates in the progression of cardiovascular diseases, such as endothelial...