Discovery of novel mRNA demethylase FTO inhibitors against esophageal cancer
A series of 1,2,3-triazole analogues as novel fat mass and obesity-associated protein (FTO) inhibitors were synthesised in this study. Among all 1,2,3-triazoles, compound C6 exhibited the most robust inhibition of FTO with an IC50 value of 780 nM. It displayed the potent antiproliferative activity a...
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Main Authors: | , , , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |