Platelet-Derived Growth Factor-BB Inhibits Intervertebral Disc Degeneration via Suppressing Pyroptosis and Activating the MAPK Signaling Pathway

• Main Authors: Weikang Zhang (Author), Yuhang Gong (Author), Xiaohang Zheng (Author), Jianxin Qiu (Author), Ting Jiang (Author), Lihua Chen (Author), Fangying Lu (Author), Xinhui Wu (Author), Fengmin Cheng (Author), Zhenghua Hong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Platelet-derived growth factor-BB (PDGF-BB) is a cytokine involved in tissue repair and tumor progression. It has been found to have expression differences between normal and degenerative intervertebral discs. However, it is not clear whether PDGF-BB has a protective effect on intervertebral disc de...