Development and validation of a method for phenobarbital in serum: anticonvulsant pharmacotherapy monitoring

• Main Authors: Palas Ateneia Dantas de Medeiros (Author), Paulo César Dantas da Silva (Author), Luana Pinto de Arruda Sales (Author), Saulo Rios Mariz (Author), Sayonara Maria Lia Fook (Author)
• Format: Book
• Published: São Paulo State University (UNESP), 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The therapeutic drug monitoring (TDM) is an important strategy for the effectiveness and safety of long-term pharmacotherapy, such as the use of phenobarbital as an anticonvulsant drug in epilepsy. In this sense, HLPC has been presented as a technique for the measurement of phenobarbital in serum. H...