Synthesis of some novel dibromo-2-arylquinazolinone derivatives as cytotoxic agents

• Main Authors: Zeinab Faghih (Author), Nasrin Rahmannejadi (Author), Razieh Sabet (Author), Kamiar Zomorodian (Author), Mohammad Asad (Author), Soghra Khabnadideh (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently the quinazoline derivatives have attracted much attention for their anticancer properties. In this study a series of new brominated quinazoline derivatives (1a-1g) were synthesized in two steps. In the first step we used N-bromosuccinimide to brominate the anthranilamid. Then in the second...