New Pyrazolo-Benzimidazole Mannich Bases with Antimicrobial and Antibiofilm Activities

• Main Authors: Christina Zalaru (Author), Florea Dumitrascu (Author), Constantin Draghici (Author), Isabela Tarcomnicu (Author), Maria Marinescu (Author), George Mihai Nitulescu (Author), Rodica Tatia (Author), Lucia Moldovan (Author), Marcela Popa (Author), Mariana Carmen Chifiriuc (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new series of pyrazolo-benzimidazole hybrid Mannich bases were synthesized, characterized by ¹H-NMR, ¹³C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro cytotoxicity of the new compounds studied on fibroblast cells showed that the newly synthesiz...