Recent Development of CDK2 Inhibitors as Anticancer Drugs: An Update (2015-2023)

• Asıl Yazarlar: Yumei Jin (Yazar), Hao Lu (Yazar), Hu Ge (Yazar), Xuben Hou (Yazar), Hao Fang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Georg Thieme Verlag KG, 2024-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Cyclin-dependent kinase 2 (CDK2) is a critical regulator of cell division and has emerged as a promising target for anticancer treatment. In this article, we summarize the structural features of CDK2 inhibitors and corresponding binding modes, in particular the noncompetitive binding modes that offe...