Transient receptor potential melastatin 2 regulates neutrophil extracellular traps formation and delays resolution of neutrophil-driven sterile inflammation

• Main Authors: Xue Cao (Author), Yanhong Li (Author), Yubin Luo (Author), Tianshu Chu (Author), Hang Yang (Author), Ji Wen (Author), Yi Liu (Author), Yi Zhao (Author), Martin Herrmann (Author)
• Format: Book
• Published: BMC, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The formation of neutrophil extracellular traps (NETs) is a process releasing into the extracellular space networks of chromatin fibers decorated with granular proteins. It is implicated in infection-related as well as sterile inflammation. Monosodium urate (MSU) crystals serve as damage-as...