Preparation and Release Profiles in Vitro/Vivo of Galantamine Pamoate Loaded Poly (Lactideco-Glycolide) (PLGA) Microspheres

• Main Authors: Liping Du (Author), Shankui Liu (Author), Guizhou Hao (Author), Li Zhang (Author), Miaomiao Zhou (Author), Yueqing Bao (Author), Bing Ding (Author), Qinyong Sun (Author), Guimin Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patient's poor compliance and the high risk of toxic effects limit the clinical use of galantamine hydrobromide. To overcome these drawbacks, the sustained-release galantamine pamoate microspheres (GLT-PM-MS) were successfully developed using an oil/water emulsion solvent evaporation method in...