Enhanced cytotoxic effect of camptothecin nanosponges in anaplastic thyroid cancer cells in vitro and in vivo on orthotopic xenograft tumors

• Main Authors: Casimiro Luca Gigliotti (Author), Benedetta Ferrara (Author), Sergio Occhipinti (Author), Elena Boggio (Author), Giuseppina Barrera (Author), Stefania Pizzimenti (Author), Mirella Giovarelli (Author), Roberto Fantozzi (Author), Annalisa Chiocchetti (Author), Monica Argenziano (Author), Nausicaa Clemente (Author), Francesco Trotta (Author), Caterina Marchiò (Author), Laura Annaratone (Author), Renzo Boldorini (Author), Umberto Dianzani (Author), Roberta Cavalli (Author), Chiara Dianzani (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anaplastic carcinoma of the thyroid (ATC) is a lethal human malignant cancer with median survival of 6 months. To date, no treatment has substantially changed its course, which makes urgent need for the development of novel drugs or novel formulations for drug delivery. Nanomedicine has enormous pot...