Mechanistic modeling projections of antibody persistence after homologous booster regimens of COVID‐19 vaccine Ad26.COV2.S in humans

• Main Authors: Anna Dari (Author), Philippe Jacqmin (Author), Yuki Iwaki (Author), Martine Neyens (Author), Mathieu Le Gars (Author), Jerald Sadoff (Author), Karin Hardt (Author), Javier Ruiz‐Guiñazú (Author), Juan José Pérez‐Ruixo (Author)
• Format: Book
• Published: Wiley, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Mechanistic model‐based simulations can be deployed to project the persistence of humoral immune response following vaccination. We used this approach to project the antibody persistence through 24 months from the data pooled across five clinical trials in severe acute respiratory syndrome...