Effect of Calcium Carbonate Encapsulation on the Activity of Orally Administered CpG Oligonucleotides

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs (CpG ODNs) stimulate immune cells via Toll-like receptor 9 (TLR9). Because oligodeoxynucleotides (ODNs) are susceptible to gastric degradation, clinical trials designed to evaluate their therapeutic utility have relied solely on pare...

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Main Authors: Neslihan Kayraklioglu (Author), Julia Scheiermann (Author), W. Gregory Alvord (Author), Dennis M. Klinman (Author)
Format: Book
Published: Elsevier, 2017-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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