Effect of Calcium Carbonate Encapsulation on the Activity of Orally Administered CpG Oligonucleotides
Synthetic oligodeoxynucleotides containing unmethylated CpG motifs (CpG ODNs) stimulate immune cells via Toll-like receptor 9 (TLR9). Because oligodeoxynucleotides (ODNs) are susceptible to gastric degradation, clinical trials designed to evaluate their therapeutic utility have relied solely on pare...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Elsevier,
2017-09-01T00:00:00Z.
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