Characterization and clinical evaluation of microsatellite instability and loss of heterozygosity within tumor-related genes in colorectal cancer

• Main Authors: Xueyun Huo (Author), Dandan Feng (Author), Shuangyue Zhang (Author), Zhenkun Li (Author), Xiaohong Li (Author), Changlong Li (Author), Meng Guo (Author), Jin Wang (Author), Zhongtao Zhang (Author), Qingxian Lu (Author), Xiaoyan Du (Author), Zhigang Bai (Author), Zhenwen Chen (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Microsatellite instability (MSI) is a biomarker for better outcomes in colorectal cancer (CRC). However, this conclusion is controversial. In addition, MSs can be a useful marker for loss of heterozygosity (LOH) of genes, but this finding has not been well studied. Here, we aimed...