Adolescent Binge Alcohol Enhances Early Alzheimer's Disease Pathology in Adulthood Through Proinflammatory Neuroimmune Activation

• 主要な著者: Alexandra Barnett (著者), Emeraghi David (著者), Aaron Rohlman (著者), Viktoriya D. Nikolova (著者), Sheryl S. Moy (著者), Ryan P. Vetreno (著者), Leon G. Coleman (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Epidemiological studies suggest that heavy alcohol use early in life is associated with increased risk for Alzheimer's disease (AD). However, mechanisms connecting AD with alcohol use have not been identified. Both heavy alcohol use and AD feature increased proinflammatory signaling. Therefore,...