Effects of long-term culture on the biological characteristics and RNA profiles of human bone-marrow-derived mesenchymal stem cells

• Main Authors: Shan Wang (Author), Ziming Wang (Author), Hongjun Su (Author), Fenglei Chen (Author), Mengjun Ma (Author), Wenhui Yu (Author), Guiwen Ye (Author), Shuizhong Cen (Author), Rujia Mi (Author), Xiaohua Wu (Author), Wen Deng (Author), Pei Feng (Author), Chenying Zeng (Author), Huiyong Shen (Author), Yanfeng Wu (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Expansion in vitro prior to mesenchymal stem cells (MSCs) application is a necessary process. Functional and genomic stability has a crucial role in stem-cell-based therapies. However, the exact expression and co-expressed profiles of coding and non-coding RNAs in human bone marrow (BM)-MSCs in vitr...