Elevated microsatellite instability at selected tetranucleotide (EMAST) repeats in gastric cancer: a distinct microsatellite instability type with potential clinical impact?

• Main Authors: Anna‐Lina Herz (Author), Sarah Wisser (Author), Meike Kohlruss (Author), Julia Slotta‐Huspenina (Author), Moritz Jesinghaus (Author), Bianca Grosser (Author), Katja Steiger (Author), Alexander Novotny (Author), Alexander Hapfelmeier (Author), Thomas Schmidt (Author), Matthias M Gaida (Author), Wilko Weichert (Author), Gisela Keller (Author)
• Format: Book
• Published: Wiley, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We investigated the clinical impact of elevated microsatellite instability at selected tetranucleotide (EMAST) repeats in the context of neoadjuvant chemotherapy (CTx) in gastric/gastro‐oesophageal adenocarcinomas. We analysed 583 resected tumours (272 without and 311 after CTx) and 142 tum...