Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway

• Main Authors: Jia Xiao (Author), Feiyue Xing (Author), Yingxia Liu (Author), Yi Lv (Author), Xiaogang Wang (Author), Ming-Tat Ling (Author), Hao Gao (Author), Songying Ouyang (Author), Min Yang (Author), Jiang Zhu (Author), Yu Xia (Author), Kwok-Fai So (Author), George L. Tipoe (Author)
• Format: Book
• Published: Elsevier, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Whether and how garlic-derived S-allylmercaptocysteine (SAMC) inhibits hepatocellular carcinoma (HCC) is largely unknown. In the current study, the role of low-density lipoprotein receptor (LDLR)-related protein 6 (LRP6) in HCC progression and the anti-HCC mechanism of SAMC was examined in clinical...