Mesenchymal stem cell-derived apoptotic bodies alleviate alveolar bone destruction by regulating osteoclast differentiation and function

• Main Authors: Xiaoyan Li (Author), Yiyang Jiang (Author), Xu Liu (Author), Jingfei Fu (Author), Juan Du (Author), Zhenhua Luo (Author), Junji Xu (Author), Ujjal Kumar Bhawal (Author), Yi Liu (Author), Lijia Guo (Author)
• Format: Book
• Published: Nature Publishing Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Periodontitis is caused by overactive osteoclast activity that results in the loss of periodontal supporting tissue and mesenchymal stem cells (MSCs) are essential for periodontal regeneration. However, the hypoxic periodontal microenvironment during periodontitis induces the apoptosis of M...