Altered Redox Mitochondrial Biology in the Neurodegenerative Disorder Fragile X-Tremor/Ataxia Syndrome: Use of Antioxidants in Precision Medicine

• Main Authors: Gyu Song (Author), Eleonora Napoli (Author), Sarah Wong (Author), Randi Hagerman (Author), Siming Liu (Author), Flora Tassone (Author), Cecilia Giulivi (Author)
• Format: Book
• Published: BMC, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract A 55-200 expansion of the CGG nucleotide repeat in the 5'-UTR of the fragile X mental retardation 1 gene (FMR1) is the hallmark of the triplet nucleotide disease known as the "premutation" as opposed to those with >200 repeats, known as the full mutation or fragile X syndr...