Signaling via the Interleukin-10 Receptor Attenuates Cardiac Hypertrophy in Mice During Pressure Overload, but not Isoproterenol Infusion

• Main Authors: Nicholas Stafford (Author), Farryah Assrafally (Author), Sukhpal Prehar (Author), Min Zi (Author), Ana M. De Morais (Author), Arfa Maqsood (Author), Elizabeth J. Cartwright (Author), Werner Mueller (Author), Delvac Oceandy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammation plays a key role during cardiac hypertrophy and the development of heart failure. Interleukin-10 (IL-10) is a major anti-inflammatory cytokine that is expressed in the heart and may play a crucial role in cardiac remodeling. Based on the evidence that IL-10 potentially reduces pathologi...